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Eccrine spiradenoma: a report of malignant transformation
C J Engel1, G E Meads, N G Joseph
1Department of Surgery, St. Joseph's Health Centre, University of Western Ontario, London.
Canadian Journal of Surgery. Journal Canadien De Chirurgie
|October 1, 1991
Summary
Malignant transformation in eccrine spiradenoma is rare, with only 16 prior cases reported. This study details a unique case of malignant eccrine spiradenoma in a young man, successfully treated with amputation and node dissection.
Area of Science:
- Dermatology
- Oncology
- Surgical Pathology
Background:
- Eccrine spiradenoma is a common benign cutaneous adnexal tumor.
- Malignant transformation within eccrine spiradenoma is exceptionally rare.
- Previous literature documents only 16 reported cases of malignant eccrine spiradenoma.
Observation:
- A 21-year-old male presented with malignant transformation of an eccrine spiradenoma on the big toe.
- Histological examination revealed two distinct components: typical eccrine spiradenoma and a transitional carcinoma.
- The tumor involved the big toe, a less common site for such a condition.
Findings:
- The case represents the 17th documented instance of malignant eccrine spiradenoma.
- Surgical treatment involved below-knee amputation and superficial inguinal lymph node dissection.
- No evidence of recurrence was observed 2 years post-surgery, indicating successful treatment.
Implications:
- This case contributes to the limited understanding of malignant eccrine spiradenoma.
- Highlights the importance of thorough histopathological evaluation for accurate diagnosis.
- Emphasizes the potential efficacy of aggressive surgical management in preventing recurrence.