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Published on: September 18, 2014
Development of gastric slow waves and effects of feeding in pre-term and full-term infants
1Division of Gastroenterology, University of Texas Medical Branch at Galveston, 77555, USA.
Insights
Preterm infants show similar gastric slow wave rhythm but reduced amplitude compared to full-term infants. Feeding methods have minimal impact on gastric electrical activity in preterm infants and none in full-term infants.
Area of Science:
- Gastroenterology
- Neonatology
- Physiology
Background:
- Gastric slow waves are crucial for digestion.
- Understanding their development in infants is vital for assessing gastrointestinal health.
- Differences may exist between preterm and full-term infants.
Purpose of the Study:
- To compare gastric slow wave development in preterm versus full-term infants.
- To evaluate the impact of feeding methods on gastric myoelectrical activity.
- To analyze electrogastrography (EGG) patterns from birth to six months.
Main Methods:
- Electrogastrography (EGG) was used to record gastric myoelectrical activity.
- Twenty-six preterm and 31 full-term infants were studied from birth to 6 months.
- Data analysis focused on slow wave frequency, power, and response to feeding.
Main Results:
- Both groups showed an increase in 2-4 cycles per minute (cpm) slow waves from birth to 4 months.
- Preterm infants exhibited reduced dominant EGG power at certain study points.
- Feeding type did not affect EGG in full-term infants; minimal, possibly non-clinical, effects were seen in preterm infants at 2 months.
Conclusions:
- Preterm infants have gastric slow waves with reduced amplitude but similar rhythmicity to full-term infants.
- Feeding methods do not significantly alter EGG patterns in either group over the 6-month period.
- These findings contribute to understanding preterm infant gastrointestinal development.
Abstract:
The aims of this study were to investigate the difference in developmental process of gastric slow waves and the effects of feeding in pre-term and full-term infants. Twenty-six pre-term and 31 full-term infants were enrolled in the study. Gastric myoelectrical activity was recorded using electrogastrography (EGG) from birth to month 6. An increase in the % of 2-4 cpm slow waves was noted in both pre-term (P < 0.01) and full-term infants (P < 0.04) from birth to month 4. The pre-term infants showed a reduced dominant EGG power at certain points of the study. (3) Breast or formula feeding resulted in no difference in the EGG in the full-term infants and showed a difference in the postprandial dominant power of the EGG in the pre-term infants only at month 2 after birth (P < 0.05) but not at other times. The gastric slow wave in pre-term infants is of a significantly reduced amplitude but similar rhythmicity. The method of feeding has no effects on the EGG in full-term infants and minimal effects (may be of non-clinical significance) on the EGG in pre-term infants as the difference was noted only at one time point during the 6-month follow-up study.
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