The structure of the lipid anchor of Campylobacter jejuni polysaccharide
Adrian T Corcoran1, Heidi Annuk, Anthony P Moran
1Department of Microbiology, National University of Ireland, Galway, Ireland.
Abstract:
Campylobacter jejuni is a leading cause of gastroenteritis in humans. Campylobacter jejuni produces extracellular polysaccharides that have been characterized structurally and shown to be independent of lipopolysaccharides. Furthermore, it has been suggested that these C. jejuni polysaccharides are capsular in nature, although their lipid anchor has not been identified. In this report, the occurrence of a lipid-linked capsular-like polysaccharide in C. jejuni is conclusively shown, and the lipid anchor identified as dipalmitoyl-glycerophosphate.
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