Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Extinction learning before trauma and subsequent posttraumatic stress.

Rachel M Guthrie1, Richard A Bryant

  • 1School of Psychology, University of New South Wales, Australia.

Psychosomatic Medicine
|March 24, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Study protocol for a controlled trial of a resilience program on psychological distress in correctional officers in Australia.

BMC psychiatry·2023
Same author

Web-Based Mind-Body Tactical Resilience Training Program for First Responders: Pre-Post Study Assessing Feasibility, Acceptability, and Usability.

JMIR formative research·2023
Same author

Association of Neural Connectome With Early Experiences of Abuse in Adults.

JAMA network open·2023
Same author

Videoconferencing-delivered psychological intervention for the treatment of COVID-19 related psychological distress in University students: study protocol for a randomised controlled trial in India.

BMC psychiatry·2022
Same author

Attachment processes in posttraumatic stress disorder: A review of mechanisms to advance theories and treatments.

Clinical psychology review·2022
Same author

The Heterogeneity of Posttraumatic Stress Disorder in DSM-5.

JAMA psychiatry·2022

Poor extinction learning before trauma exposure predicts persistent posttraumatic stress. Reduced ability to extinguish conditioned emotional responses may increase vulnerability to developing posttraumatic stress disorder (PTSD).

Area of Science:

  • Psychology
  • Neuroscience
  • Trauma Studies

Background:

  • Persistent stress reactions are linked to impaired extinction learning.
  • A poor capacity for extinction learning may predispose individuals to posttraumatic stress disorder (PTSD).

Purpose of the Study:

  • To investigate if deficits in extinction learning before trauma exposure are a risk factor for persistent posttraumatic stress.
  • To determine the predictive value of pre-trauma extinction learning on posttraumatic stress severity.

Main Methods:

  • Assessed 84 firefighters during cadet training (pre-trauma) and 70 after 24 months of active duty (post-trauma).
  • Measured posttraumatic stress symptoms before and after trauma exposure.
  • Obtained skin conductance and corrugator electromyogram (EMG) responses during fear conditioning and extinction paradigms pre-trauma.

Related Experiment Videos

Main Results:

  • Reduced extinction of a conditioned corrugator EMG response before trauma exposure predicted 31% of the variance in posttraumatic stress severity.
  • This finding highlights the role of emotional response extinction in trauma outcomes.

Conclusions:

  • Reduced extinction of conditioned emotional responses is a potential vulnerability factor for posttraumatic stress.
  • This study provides preliminary evidence supporting impaired extinction learning as a risk factor for PTSD.