Related Experiment Video
Updated: Aug 9, 2026

Optimized System for Cerebral Perfusion Monitoring in the Rat Stroke Model of Intraluminal Middle Cerebral Artery Occlusion
Published on: February 17, 2013
A method to reduce saline and heparin in intraoperative cerebral angiography: a preliminary report
Futoshi Mihara1, Takashi Yoshiura, Tomoyuki Noguchi
1Department of Clinical Radiology, Graduate School of Medical Sciences, Kyushu University, Fukuoka 812-8582, Japan.
Purpose:
To reduce saline and heparin in continuous catheter perfusion in intraoperative cerebral angiography, a method using a syringe pump was tried.
Materials And Methods:
Ten patients with brain arteriovenous malformation (AVM) underwent intraoperative cerebral angiography. Seven internal carotid arteries (ICAs) and six vertebral arteries (VAs) were catheterized in these patients. Continuous catheter perfusion was performed at a low rate of 3 mL/hr with saline containing 8,000 units of heparin per liter using a syringepump.
Results:
Mean duration of catheter perfusion was 8.3 +/- 4.0 hrs (range, 3.0 to 15.7 hrs). Mean volume of saline was 25.0 +/- 11.9 mL (range, 9 to 47 mL) per catheter. Mean dosage of heparin was 200.0 +/- 94.9 units (range, 72 to 376 units) per catheter. No complications due to intraoperative angiography were observed in this trial.
Conclusion:
Reduction of the saline volume and heparin dosage was possible in intraoperative cerebral angiography by the continuous perfusion of a small amount of high-concentration heparinized saline using a syringe pump.
