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Updated: Jul 31, 2026
13:19
Microarray-based Identification of Individual HERV Loci Expression: Application to Biomarker Discovery in Prostate Cancer
Published on: November 2, 2013
Cancer biomarkers: knowing the present and predicting the future
Sabarni K Chatterjee1, Bruce R Zetter
1Program in Vascular Biology, Children's Hospital, Boston and Harvard Medical School, 300 Longwood Avenue, Boston, MA 02115, USA. Sabarni.Chatterjee@childrens.harvard.edu
Future Oncology (London, England)
|March 25, 2006
Summary
Cancer biomarker discovery is crucial for early detection and personalized treatment. Advanced technologies enable the development of reliable tests for improved cancer management and patient outcomes.
Area of Science:
- Oncology
- Biomarker Research
- Genomics and Proteomics
Background:
- Cancer biomarker discovery is a key research area, driven by successes like prostate-specific antigen (PSA) for prostate cancer screening.
- Biomarkers are essential for cancer diagnosis, monitoring progression, predicting recurrence, and evaluating treatment effectiveness.
Purpose of the Study:
- To highlight the significance of cancer biomarkers in modern research and clinical practice.
- To discuss the role of emerging technologies in advancing biomarker development.
Main Methods:
- Leveraging advanced genomic and proteomic technologies, including DNA and tissue microarrays.
- Utilizing techniques such as two-dimensional gel electrophoresis, mass spectrometry, and protein assays.
- Employing sophisticated bioinformatic tools for data analysis and biomarker identification.
Main Results:
- New technologies facilitate the development of reliable biomarkers for predicting cancer outcomes.
- Biomarkers can significantly aid in cancer management and treatment decisions.
Conclusions:
- The development of accurate cancer biomarkers is transforming clinical decision-making.
- Future applications may include non-invasive serum or urine tests for all cancer phases, potentially replacing invasive procedures.
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