Related Experiment Videos
Extra-anogenital HPV16-related bowenoid papulosis
J J Grob1, H Zarour, J Jacquemier
1Service de Dermatologie, Hôpital Ste Marguerite, Marseilles, France.
Abstract:
In this report we describe a case of bowenoid papulosis (BP) on the face of a 44 year old Algerian man. To our knowledge this is the first reported case of isolated extragenital BP. The presence of type 16 human papilloma virus was demonstrated by in situ hybridisation. This case underscores that multiple HPV-induced severe intraepithelial neoplasia, the so-called BP, is not restricted to the anogenital area.
Insights
This report details the first known case of isolated extragenital Bowenoid Papulosis (BP) on a man's face. Human Papillomavirus type 16 was detected, confirming HPV-induced neoplasia can occur outside the anogenital region.
Area of Science:
- Dermatology
- Oncology
- Virology
Background:
- Bowenoid Papulosis (BP) is a rare condition characterized by severe intraepithelial neoplasia.
- Typically, BP is found in the anogenital region, often associated with Human Papillomavirus (HPV) infection.
Observation:
- A case of isolated extragenital Bowenoid Papulosis (BP) on the face of a 44-year-old Algerian man is presented.
- This represents the first documented instance of BP occurring exclusively in a non-anogenital location.
Findings:
- In situ hybridization confirmed the presence of Human Papillomavirus type 16 (HPV-16) in the affected facial lesions.
- The findings indicate that HPV-induced severe intraepithelial neoplasia, or BP, is not confined to the anogenital area.
Implications:
- This case expands the known clinical spectrum and anatomical distribution of Bowenoid Papulosis.
- It highlights the importance of considering HPV-related neoplasia in extragenital skin lesions, even in the facial area.
- Further research may be warranted to understand the specific risk factors and management of facial BP.