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Updated: Aug 9, 2026
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An Efficient and Simple Method to Establish NK and T Cell Lines from Patients with Chronic Active Epstein-Barr Virus Infection
Published on: March 30, 2018
[Fatal fulminant Epstein-Barr virus hepatitis]
M Lazrek1, F Boitrelle, A Dewilde
1Service de Virologie/UPRES EA 3610, CHRU de Lille, Université de Lille 2.
Annales De Biologie Clinique
|March 25, 2006
Summary
Infectious mononucleosis, a common illness, can rarely cause fatal liver failure. This case highlights a rare instance of fulminant hepatitis following Epstein-Barr virus infection in a teenager.
Area of Science:
- Hepatology
- Virology
- Infectious Diseases
Background:
- Infectious mononucleosis is typically a benign condition.
- Hepatic cytolysis is a frequent finding in infectious mononucleosis.
- Fulminant hepatitis is an uncommon complication.
Observation:
- A 15-year-old male presented with primary Epstein-Barr virus (EBV) infection.
- The patient developed severe liver dysfunction.
- The case progressed to fatal fulminant hepatitis.
Findings:
- This report details a rare fatal outcome of EBV infection.
- Demonstrates a case of fulminant hepatitis secondary to primary EBV infection.
- Highlights the potential for severe hepatic complications.
Implications:
- Underscores the importance of monitoring liver function in EBV infections.
- Suggests EBV can rarely lead to life-threatening hepatitis.
- Contributes to understanding the spectrum of EBV-related liver disease.
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