Related Experiment Video
Updated: Aug 9, 2026

An Experimental Human DIEP Flap Model to Investigate Preservation Strategies for Vascularized Composite Allografts and Free Flaps
Published on: December 5, 2025
Complications associated with breast reconstruction using a perforator flap compared with a free TRAM flap
Adena S Scheer1, Christine B Novak, Peter C Neligan
1Faculty of Medicine and, University of Toronto, Toronto, Ontario, Canada.
Abstract:
This study evaluated the recipient and donor site complications associated with breast reconstruction using a deep inferior epigastric artery perforator flap (DIEAP) flap compared with a free TRAM flap. The charts of 108 patients who underwent breast reconstruction using these techniques were reviewed. There were 130 flaps. Patients with free TRAM flaps had a significantly longer hospital stay (P=0.003). There were significantly more cases of fat necrosis in the unilateral DIEAP flaps (P=0.001). In patients who were overweight or obese (body mass index >25 kg/m), there were significantly more breast complications (P=0.006). There were more cases of abdominal flap necrosis at the donor site in smokers (P = 0.018) and the diabetic patients (P=0.013). This study suggests that postoperative complications are related to patient comorbidities, and personal factors and should be considered when selecting the most appropriate reconstructive option.
