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Related Experiment Videos

[Can optic perineuritis be triggered by Mycobacterium tuberculosis?].

M Jacob1, L Kodjikian, B Ponceau

  • 1Service d'Ophtalmologie, Hôpital de la Croix-Rousse, Lyon, France. maud.jacob@laposte.net

Journal Francais D'Ophtalmologie
|March 25, 2006
PubMed
Summary

A patient with miliary tuberculosis developed optic disc swelling, diagnosed as optic perineuritis. Treatment adjustment led to recovery, highlighting diagnostic considerations for this condition.

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Area of Science:

  • Ophthalmology
  • Neurology
  • Infectious Diseases

Background:

  • Miliary tuberculosis can present with diverse neurological complications.
  • Optic disc swelling (papilledema) requires careful etiological investigation, especially when visual acuity is preserved.

Observation:

  • A 38-year-old woman undergoing treatment for miliary tuberculosis developed isolated swelling of the left optic disc.
  • The clinical presentation mimicked papilledema but without associated visual impairment.

Findings:

  • Optic perineuritis was diagnosed based on clinical findings and response to treatment.
  • Antibiotic regimen was modified, leading to a gradual resolution of optic disc swelling.

Implications:

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  • This case underscores the importance of considering optic perineuritis in the differential diagnosis of optic disc edema in patients with tuberculosis.
  • It highlights the diagnostic challenges and potential etiologies, including infectious, toxic, and dysimmune mechanisms.
  • Management involves adapting antimicrobial therapy and considering broader neurological workup.