Related Experiment Video
Updated: Aug 9, 2026

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
Published on: August 18, 2017
Absolute configurations of brominated sesquiterpenes determined by vibrational circular dichroism
Kenji Monde1, Tohru Taniguchi, Nobuaki Miura
1Division of Biological Sciences, Graduate School of Science, Frontier Research Center for the Post-Genomic Science and Technology, Hokkaido University, Sapporo 001-0021, Japan. kmonde@glyco.sci.hokudai.ac.jp
Abstract:
Two brominated sesquiterpenes, majapolene B (1) and acetylmajapolene B (2), isolated from the red algal genus Laurencia were investigated using vibrational circular dichroism (VCD). The ab initio theoretical VCD and IR calculations of 1 and 2 were performed by density functional theory (DFT) using the B3PW91/6-31G(d,p) basis set. The experimental VCD spectra and corresponding population-weighted theoretical VCD spectra were found to be in excellent agreement in CCl(4) solution in the 1800-850 cm(-1) region, which allowed unambiguous determination of the absolute configurations of (-)-1 and (-)-2 as 7S,10S and 7S,10S, respectively.
More Related Videos
08:49Multimodal Nonlinear Hyperspectral Chemical Imaging Using Line-Scanning Vibrational Sum-Frequency Generation Microscopy
Published on: December 1, 2023
08:54Vibrational Spectra of a N719-Chromophore/Titania Interface from Empirical-Potential Molecular-Dynamics Simulation, Solvated by a Room Temperature Ionic Liquid
Published on: January 25, 2020
Related Concept Videos
NMR Spectroscopy of Benzene Derivatives
¹H NMR of Conformationally Flexible Molecules: Temporal Resolution
Spin–Spin Coupling Constant: Overview
Qualitatively, any spin plus-half nucleus polarizes the spins of its electrons to the minus-half state. Consequently, the paired electron in the hydrogen–carbon bond must have a...
¹H NMR of Conformationally Flexible Molecules: Variable-Temperature NMR
Stereoisomerism of Cyclic Compounds
UV–Vis Spectroscopy: Woodward–Fieser Rules