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Detection of Neutralization-sensitive Epitopes in Antigens Displayed on Virus-Like Particle (VLP)-Based Vaccines Using a Capture Assay
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Identification of a gonococcal antigen important in the human immune response
1Venereal Disease Research Laboratory, National Communicable Disease Center, U.S. Department of Health, Education, and Welfare, Atlanta, Georgia 30333.
Infection and Immunity
|February 1, 1970
Abstract:
An antigen isolated from Neisseria gonorrhoeae protoplasm reacted well in a flocculation procedure with sera from 86% of the females and 68% of the males infected with gonorrhea; the reactions with sera from presumed noninfected individuals were approximately 12%.
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Antigens Involved in Adaptive Immunity
An antigen is any substance the immune system identifies as foreign and potentially harmful to the body, prompting an immune response. Antigens have two functional properties: immunogenicity and reactivity. Immunogenicity is the ability of an antigen to stimulate a specific immune response. At the same time, reactivity describes the antigen's ability to react with the cells and antibodies produced in response to it.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Complete Antigens
Complete antigens possess both immunogenicity and reactivity.
Cross-reactivity
Overview

