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Updated: Aug 9, 2026

Immuno-fluorescence Assay of Leptospiral Surface-exposed Proteins
Published on: July 1, 2011
Latent syphilis: immunoglobulins reactive in immunofluorescence and other serological tests
A J Julian1, L C Logan, L C Norins
1Venereal Disease Research Laboratory, Center for Disease Control, Atlanta, Georgia 30333.
Abstract:
Study of sera from 69 patients with untreated or inadequately treated latent syphilis revealed that immunoglobulin (Ig)G antibodies made up the bulk of the fluorescent treponemal antibody-absorption (FTA-ABS)-test reactivity found in the sera. IgM and IgA antibodies also contributed in some cases. Venereal Disease Research Laboratory slide-test reactivity was found in both 19 and 7S serum fractions, whereas Treponema pallidum immobilization-test reactivity was found mainly in the 7S fraction.
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