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Updated: Aug 9, 2026
Sexual Transmission of American Trypanosomes from Males and Females to Naive Mates
Published on: January 27, 2019
[Analysis of molecular profiles among Trypanozoon species and subspecies by MGE-PCR method]
Feng-jun Li1, Jia-yu Zheng, Wan-zhong Jia
1Center for Parasitic Organisms, School of Life Sciences, Zhongshan (Sun Yat-Sen) University, Guangzhou, China.
Objective:
To analyze the relationship between genetic variability and evolution among Trypanosoma brucei (including T. b. brucei, T. b. rhodesiense and T. b. gambiense), T. evansi and T. equiperdum isolates.
Methods:
Genomic DNAs of 26 trypanosome isolates were amplified by a mobile genetic elements (MGE) -PCR technique and cluster analysis was performed based on the molecular profiles with Neighbor-Joining method.
Results:
The genetic variability among trypanosome isolates examined was obvious with an average genetic distance of 41.2% (ranged from 0 to 100%). Similarity coefficient among T. brucei isolates was 41.15% which was lower than that between T. evansi and T. equiperdum isolates. The closest relationship was found between T. evansi and T. brucei isolates with a similarity coefficient of 62.94%. The genetic variability between T. b. rhodesiense and T. b. brucei isolates was higher than that among T. b. gambiense isolates.
Conclusion:
Species and subspecies in Trypanozoon displayed a higher genetic variability; T. equiperdum isolates collected from China and from South America, and T. evansi isolates from China and from South America, should have a similar origin.
