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Related Experiment Videos

Diarrheal disease during Operation Desert Shield.

K C Hyams1, A L Bourgeois, B R Merrell

  • 1Epidemiology Division, U.S. Naval Medical Research Institute, Bethesda, Md.

The New England Journal of Medicine
|November 14, 1991
PubMed
Summary

Diarrheal disease caused by drug-resistant bacteria like E. coli and Shigella significantly impacted U.S. troops during Operation Desert Shield, leading to widespread illness and duty impairment.

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Area of Science:

  • Military Medicine
  • Infectious Diseases
  • Epidemiology

Background:

  • Infectious diseases pose a significant threat to military forces in combat zones.
  • Operation Desert Shield experienced numerous outbreaks of diarrhea among U.S. forces.
  • This study evaluated causes and risk factors for diarrheal disease in U.S. troops in Saudi Arabia.

Purpose of the Study:

  • To identify the causative agents of diarrheal disease in U.S. military personnel.
  • To assess the antibiotic resistance patterns of identified pathogens.
  • To determine the impact of diarrheal illness on troop readiness.

Main Methods:

  • Collected stool cultures from 432 military personnel with gastrointestinal symptoms.
  • Administered questionnaires to 2022 soldiers regarding diarrheal disease and its effects.

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  • Analyzed clinical and epidemiological data to identify risk factors and pathogens.
  • Main Results:

    • Bacterial enteric pathogens were identified in 49.5% of troops with gastroenteritis.
    • Enterotoxigenic Escherichia coli and Shigella sonnei were the most common pathogens.
    • High rates of antibiotic resistance were observed, with all isolates sensitive to norfloxacin and ciprofloxacin.
    • 57% of troops reported at least one episode of diarrhea, and 20% were temporarily unable to perform duties.

    Conclusions:

    • Gastroenteritis due to drug-resistant enterotoxigenic E. coli and Shigella was a major issue.
    • Diarrheal illness frequently interfered with the operational duties of U.S. troops.
    • Antibiotic resistance patterns highlight the need for effective treatment strategies in deployed forces.