Related Experiment Video

Updated: Aug 9, 2026

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis
06:35

An Immunohistopathologic Study to Profile the Folate Receptor Beta Macrophage and Vascular Immune Microenvironment in Giant Cell Arteritis

Published on: February 8, 2019

[Pseudo-autoinflammatory attacks of temporal arteritis]

A Grasland1, G Galidie, M Grossin

  • 1Service de médecine interne, APHP, hôpital Louis-Mourier, 178, rue des Renouillers, 92700 Colombes, France. anne.grasland@lmr.aphp.fr

La Revue De Medecine Interne
|March 28, 2006
PubMed
Abstract

Insights

Temporal arteritis, a chronic condition, can present with rare, acute auto-inflammatory attacks. These spontaneous flares, though uncommon, may be underestimated in clinical practice.

Area of Science:

  • Rheumatology
  • Internal Medicine
  • Vascular Inflammation

Background:

  • Temporal arteritis is typically a chronic autoimmune condition.
  • Characterized by persistent inflammation of arteries, particularly the temporal artery.

Observation:

  • A case study of a 74-year-old woman with temporal arteritis.
  • The patient experienced two distinct acute episodes of the disease.
  • Symptoms included headache, fever, and systemic inflammatory markers.

Findings:

  • These acute episodes of temporal arteritis resolved spontaneously.
  • The presentation suggests a potential for auto-inflammatory attacks in temporal arteritis.
  • Such attacks are considered rare and possibly underdiagnosed.

Implications:

  • Highlights the need to consider acute, self-limiting presentations of temporal arteritis.
  • Suggests further research into the pathophysiology of auto-inflammatory mechanisms in vasculitis.
  • May impact diagnostic criteria and management strategies for temporal arteritis.

More Related Videos

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model07:40

Experimental Autoimmune Uveitis: An Intraocular Inflammatory Mouse Model

Published on: January 12, 2022

Related Concept Videos

Transient Ischemic Attack l: Introduction01:26

Transient Ischemic Attack l: Introduction

A transient ischemic attack (TIA) is a brief episode of neurological dysfunction caused by a temporary, focal reduction in cerebral blood flow. Although symptoms resemble those of an ischemic stroke, the interruption in perfusion is short-lived and does not cause permanent infarction. TIAs are clinically important because they often serve as early warning events for future stroke.Mechanisms of Transient Cerebral IschemiaTransient cerebral ischemia may arise through several mechanisms. One...
Encephalitis ll: Pathophysiology01:26

Encephalitis ll: Pathophysiology

Encephalitis is inflammation of the brain parenchyma caused by direct viral invasion or immune-mediated mechanisms triggered by infections or tumors. Both processes lead to neuronal injury, disrupted neurotransmission, and diverse neurological symptoms, often with overlapping clinical and pathological features.Autoimmune EncephalitisIn autoimmune encephalitis, antibodies target neuronal antigens on cell surfaces, synapses, or within neurons. A key example is anti-NMDAR encephalitis, which can...
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...
Assessing Body Temperature - Temporal Artery01:19

Assessing Body Temperature - Temporal Artery

Here is a stepwise guide to assessing the body temperature at the temporal artery using a temporal artery thermometer
Step 1: Perform hand hygiene and don a fresh pair of gloves to prevent cross-infection and ensure patient safety.
Step 2: Explain the procedure to the patient to establish trust. Clear communication establishes trust with the patient, ensures they understand what to expect, promotes cooperation, and enhances comfort during the procedure.  
Step 3: Assess the patient's forehead...
Acute Inflammation I: Inflammatory Response01:26

Acute Inflammation I: Inflammatory Response

Acute inflammation is a rapid, short-lived physiological response to tissue injury or infection, designed to eliminate harmful agents and initiate repair. This tightly regulated process typically lasts from minutes to several days and is triggered by factors such as microbial invasion, physical trauma, or chemical injury.Recognition and Mediator ReleaseThe inflammatory response begins when resident immune cells—such as mast cells, macrophages, and dendritic cells—detect damage-associated...
Chronic Inflammation: Introduction01:12

Chronic Inflammation: Introduction

Chronic inflammation is a prolonged, dysregulated immune response that persists for weeks to years when the inciting stimulus is difficult to eradicate or when self‑antigens drive ongoing reactivity. Morphologically, it is defined by mononuclear cell infiltration, progressive tissue destruction, and concurrent attempts at healing via angiogenesis and fibrosis. Compared with acute inflammation, edema is less prominent while cellular infiltration predominates; triggers include persistent...