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Published on: April 8, 2013
Left ventricular muscle band (VMB): thoughts on its physiologic and clinical implications
1Division of Cardiothoracic Surgery, Washington University School of Medicine, 660 S. Euclid Ave., Box 8234, St. Louis, MO 63110, USA. schuesslerd@wustl.edu
Insights
The ventricular muscle band (VMB) is not activated sequentially, but its contraction and relaxation may still be sequential. This sequential function is crucial for optimal cardiac electromechanical system performance.
Area of Science:
- Cardiology
- Cardiac Electrophysiology
- Cardiac Anatomy
Background:
- The ventricular muscle band (VMB) is a continuous myocardial structure.
- Previous evidence suggested a potential sequential contraction pattern along the VMB course.
Purpose of the Study:
- To investigate the activation sequence of the ventricular muscle band.
- To explore the functional implications of the VMB's activation and contraction patterns.
Main Methods:
- Analysis of the Purkinje system's activation programming.
- Consideration of cardiac action potential duration and repolarization.
Main Results:
- The VMB is not activated sequentially along its anatomical course.
- Activation proceeds broadly from endocardium to epicardium and apex to base.
- Sequential contraction and relaxation are possible despite non-sequential activation, dependent on contraction and repolarization duration.
Conclusions:
- The ventricular muscle band's activation sequence differs from its potential contraction sequence.
- Sequential VMB function is achievable through specific electrophysiological properties.
- VMB function is integral to the overall electromechanical system of the heart, ensuring optimal performance.
Abstract:
Although the ventricular muscle band (VMB) is formed by one continuous band of myocardium and there is some evidence to suggest that it may contract sequentially along its course from the right ventricle, through the septum, then along its basoapical left ventricular spiral, the structure is not activated in this sequence. Activation as programmed by the fully developed Purkinje system proceeds broadly and directly from endocardium to epicardium and from apex to base. Although not activated sequentially along its course, the band may still contract and relax sequentially if there is a progressive lengthening of the contraction duration in association with a nonuniform lengthening of the cardiac fiber action potential (repolarization) duration. Also, the systolic and diastolic functions of the band should be considered as part of a complex, integrated electromechanical system in which the activation is programmed to ensure optimal function.
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