Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Left ventricular function after exercise training in young men.

Ana Clara Tude Rodrigues1, Joicely de Melo Costa, Guilherme Barretto Alves

  • 1Heart Institute (InCor), HC, FMUSP, São Paulo, Brazil. claratude@yahoo.com

The American Journal of Cardiology
|March 28, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Variability in Cardiac Stress Test Interpretation: Agreement Between Enrollment Sites and Core Laboratories in the Global ISCHEMIA Trial.

Circulation. Population health and outcomes·2026
Same author

Position Statement on Multimodal Cardiac Imaging in Patients with Systemic Diseases - 2026.

Arquivos brasileiros de cardiologia·2026
Same author

Integrated Hemodynamic Measures of Cardiac Function and Association With Clinical Outcomes.

JACC. Advances·2026
Same author

Reference Echocardiographic Values for Cardiac Chambers in Brazil: A Multiregional, Multi-Racial Study.

Arquivos brasileiros de cardiologia·2026
Same author

Additive prognostic value of functional performance to coronary artery anatomy: the ISCHEMIA trial.

European heart journal. Cardiovascular Imaging·2026
Same author

Safety and Efficacy of Exercise-based Cardiac Rehabilitation in Patients with Refractory Angina.

Arquivos brasileiros de cardiologia·2026
Same journal

Real-World Effectiveness and Tolerability of Sacubitril/Valsartan in Octogenarian Patients With Heart Failure: Results From the PARACHUTER Study.

The American journal of cardiology·2026
Same journal

ECG-Guided Conduction Pathways as a Lever to Shorten Post-TAVI Hospitalization.

The American journal of cardiology·2026
Same journal

Cystatin-C versus creatinine and kidney function in heart failure with preserved ejection fraction: a SOGALDI-PEF analysis.

The American journal of cardiology·2026
Same journal

Balloon-expandable versus Self-expanding Valves in Patients with Small Aortic Annuli Undergoing Transcatheter Aortic Valve Replacement.

The American journal of cardiology·2026
Same journal

Drug-Coated Balloons versus Drug-Eluting Stents following Coronary Atherectomy in Severely Calcified Lesions: A Systematic Review and Meta-Analysis.

The American journal of cardiology·2026
Same journal

Prehospital Statin Therapy and Outcomes in ST-Elevation Myocardial Infarction Undergoing Primary Percutaneous Coronary Intervention.

The American journal of cardiology·2026
See all related articles

Regular aerobic exercise increases heart muscle mass and improves cardiac function in healthy men. Moderate-intensity training enhances myocardial velocities and alters blood flow dynamics, demonstrating significant cardiovascular adaptations.

Area of Science:

  • Cardiology
  • Exercise Physiology
  • Echocardiography

Background:

  • Longitudinal studies on exercise-induced cardiac changes in healthy individuals are limited.
  • Understanding cardiac adaptations to endurance training in non-athletes is crucial.

Purpose of the Study:

  • To evaluate the effects of 6 months of moderate-intensity aerobic training on cardiac structure and function in sedentary men.
  • To assess changes using standard and tissue Doppler echocardiography.

Main Methods:

  • 23 sedentary men (mean age 31.1 years) underwent 6 months of moderate aerobic training (1 hr/day, 3x/week).
  • Evaluated using standard echocardiography and tissue Doppler imaging.
  • Assessed left ventricular (LV) systolic and diastolic function, myocardial velocities (Sm, Em, Am), and cardiac dimensions.

Related Experiment Videos

Main Results:

  • Significant increase in peak oxygen consumption (14.5%) and decrease in resting heart rate.
  • Increased septal and posterior wall thickness, leading to a 15% increase in LV mass index.
  • Improved LV diastolic function (increased E/A ratio) and enhanced myocardial systolic (Sm) and early diastolic (Em) velocities.
  • No significant changes in LV diameters, stroke volume, or ejection fraction.

Conclusions:

  • Physiologic left ventricular hypertrophy occurs in healthy young men following regular aerobic exercise.
  • Tissue Doppler echocardiography reveals improved LV function, specifically enhanced myocardial velocities, despite unchanged standard echocardiographic indices.
  • Exercise-induced cardiac adaptations involve altered diastolic filling patterns and improved myocardial contractility.