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Updated: Aug 9, 2026

Visualization of Endoplasmic Reticulum Subdomains in Cultured Cells
Published on: February 18, 2014
Theory of spatial patterns of intracellular organelles
Abstract:
Here we report on a generalized theory of spatial patterns of intracellular organelles, which are controlled by cells using cytoskeleton-based movements powered by molecular motors. The theory reveals that organelles exhibit one of the four distinct, stable patterns, namely aggregation, hyperdispersion, radial dispersion, and areal dispersion. Existence of specific patterns is determined by the contributions from three transport mechanisms, characterized by two Peclet numbers. The predicted patterns compare well with experimental data. This study provides a firm theoretical ground for classification of spatial patterns of organelles and understanding their regulation by cells.
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