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Published on: November 4, 2018
Generation of cloned transgenic pigs rich in omega-3 fatty acids
Liangxue Lai1, Jing X Kang, Rongfeng Li
1Division of Animal Science, University of Missouri-Columbia, Columbia, Missouri 65211, USA.
Abstract:
Meat products are generally low in omega-3 (n-3) fatty acids, which are beneficial to human health. We describe the generation of cloned pigs that express a humanized Caenorhabditis elegans gene, fat-1, encoding an n-3 fatty acid desaturase. The hfat-1 transgenic pigs produce high levels of n-3 fatty acids from n-6 analogs, and their tissues have a significantly reduced ratio of n-6/n-3 fatty acids (P < 0.001).
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