Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Human papillomavirus type 58 DNA sequence.

Y Kirii¹, S Iwamoto, T Matsukura

¹Kanebo Institute for Cancer Research, Osaka, Japan.

|November 1, 1991

Summary

This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Middle-ear carcinoid tumour metastasising to the parapharyngeal space and the parotid gland.

The Journal of laryngology and otology·2022

Same author

Phonon Lifetime Observation in Epitaxial ScN Film with Inelastic X-Ray Scattering Spectroscopy.

Physical review letters·2018

Same author

Gonadotropin levels in urine during early postnatal period in small for gestational age preterm male infants with fetal growth restriction.

Journal of perinatology : official journal of the California Perinatal Association·2017

Same author

Response to thyrotropin-releasing hormone stimulation tests in preterm infants with transient hypothyroxinemia of prematurity.

Journal of perinatology : official journal of the California Perinatal Association·2015

Same author

FOLFIRI plus bevacizumab as second-line therapy in patients with metastatic colorectal cancer after first-line bevacizumab plus oxaliplatin-based therapy: the randomized phase III EAGLE study.

Annals of oncology : official journal of the European Society for Medical Oncology·2015

Same author

Ultralow mode-volume photonic crystal nanobeam cavities for high-efficiency coupling to individual carbon nanotube emitters.

Nature communications·2014

The complete nucleotide sequence of human papillomavirus type 58 (HPV 58) was determined. This study reveals HPV 58

Area of Science:

Virology
Molecular Biology
Genomics

Background:

Human papillomavirus (HPV) infections are linked to various cancers, particularly cervical cancer.
Understanding the genetic makeup of different HPV types is crucial for developing diagnostic and therapeutic strategies.

Purpose of the Study:

To determine the complete nucleotide sequence of human papillomavirus type 58 (HPV 58).
To analyze the genomic organization and evolutionary relationships of HPV 58 with other HPV types.

Main Methods:

Cloning of HPV 58 DNA from an invasive cervical carcinoma.
Determination of the complete nucleotide sequence (7824 nucleotides).
Comparative analysis of nucleotide and amino acid sequences with other HPV types.

Related Experiment Videos

Main Results:

The HPV 58 genome has 7824 nucleotides with 37.9% GC content.
HPV 58 shares conserved regulatory signal sequences with other genital HPVs.
Extensive homology (77%) was observed between HPV 58 and HPV 33 at the nucleotide level.
Amino acid sequence analysis shows HPV 58 is closely related to HPVs 16, 31, and 33, forming a distinct group within HPV.

Conclusions:

HPV 58 exhibits a genome organization similar to other HPVs.
HPV 58 is evolutionarily closely related to HPV types 16, 31, and 33.
These findings contribute to the classification and understanding of HPV diversity and evolution.