Related Experiment Video
Updated: Aug 9, 2026

Isolation and Purification of Fungal β-Glucan as an Immunotherapy Strategy for Glioblastoma
Published on: June 2, 2023
Inedible mushrooms: a good source of biologically active substances
Dang Ngoc Quang1, Toshihiro Hashimoto, Yoshinori Asakawa
1Faculty of Pharmaceutical Sciences, Tokushima Bunri University, Yamashiro-cho, Tokushima 770-8514, Japan.
Abstract:
In the course of our investigation on biologically active substances from inedible mushrooms in Japan, Germany, and Vietnam, we studied the chemical constituents of 22 species belonging to five families: Scutigeraceae, Polyporaceae, Xylariaceae, Thelephoraceae, and Paxillaceae. Various types of chemical substances were purified and characterized based on the modern spectroscopic methods and also on chemical reactions. These metabolites have shown a broad activity in many biological systems, such as antimicrobial, nematicidal, inhibition of NO production, anti-human immunodeficiency virus, tumor necrosis factor-alpha, and antioxidant activities. These isolated metabolites did not only show interesting activities, but also are employed as chemical markers supported for chemosystematics of these families. This review paper deals with the chemical constituents of 22 species, their biological activities, and also a discussion on chemosystematics.
Related Concept Videos
Fungal Group Zygomycota
Biological Methods for Microbial Control
Biodeterioration
Overview of Fungi
Microbes in the Production of Fermented Foods
Bioplastics
