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[Susceptibility to infection in patients with diabetes mellitus]
1Isala Klinieken, locatie Weezenlanden, afd. Interne Geneeskunde, Postbus 10.500, 8000 GM Zwolle. h.j.g.bilo@isala.nl
Abstract:
A variety of possible mechanisms that might explain such susceptibility are described in the literature. Still, definite explanations for and actual proof of this supposed susceptibility remains scarce. Most evidence has been provided for urinary tract infections, bacterial skin infections, and skin and mucosal Candida infections. A recent Dutch study among patients presenting to general practitioners provides further evidence for the increased susceptibility to this kind of infections, but also revealed a more frequent occurrence of lower respiratory tract infections and other skin or mucosal mycotic infections. Furthermore, there was an increased risk of prostatitis.
Insights
Research suggests an increased susceptibility to various infections, including urinary tract, skin, and respiratory infections. Further studies are needed to confirm these findings and understand the underlying mechanisms.
Area of Science:
- Medical Mycology
- Infectious Diseases
- Epidemiology
Background:
- Limited evidence exists for the mechanisms behind increased susceptibility to certain infections.
- Previous research has focused on urinary tract, bacterial skin, and mucosal Candida infections.
Discussion:
- A Dutch study indicates heightened susceptibility to common infections and a greater incidence of lower respiratory tract and other fungal infections.
- The study also identified an elevated risk of prostatitis.
Key Insights:
- Increased susceptibility to infections is suggested but lacks definitive proof.
- Evidence points towards urinary tract, bacterial skin, and mucosal Candida infections as areas of concern.
- New evidence suggests increased risk for lower respiratory tract infections, other fungal infections, and prostatitis.
Outlook:
- Further research is required to elucidate the mechanisms of increased infection susceptibility.
- Investigating the link between susceptibility and conditions like prostatitis is crucial.
- Longitudinal studies could provide more robust evidence on infection risks.
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