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Updated: Aug 9, 2026

Construction of Model Lipid Membranes Incorporating G-protein Coupled Receptors (GPCRs)
Published on: February 5, 2022
Spectrin-phospholipid interactions. Existence of multiple kinds of binding sites?
Michał Grzybek1, Anna Chorzalska, Ewa Bok
1University of Wrocław, Institute of Biochemistry and Molecular Biology, Poland.
Abstract:
The object of this paper is to review briefly the studies on the interactions of erythroid and non-erythroid spectrins with lipids in model and natural membranes. An important progress on the identification of lipid-binding sites has recently been made although many questions remain still unanswered. In particular, our understanding of the physiological role of such interactions is still limited. Another important issue is the occurrence of spectrins in membrane rafts, how they are attached to the raft and what is their function in rafts.
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