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Virus fitness: concept, quantification, and application to HIV population dynamics

M E Quiñones-Mateu1, E J Arts

  • 1Department of Molecular Genetics, Section Virology, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue/NN10, Cleveland, OH 44195, USA. quinonm@ccf.org

Current Topics in Microbiology and Immunology
|March 30, 2006
PubMed
Summary

Viral fitness, crucial for understanding viral evolution, is examined using human immunodeficiency virus (HIV). This study explores how viral quasispecies and fitness impact HIV dynamics, disease, and treatment.

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