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Expression of Na,K-ATPase isoforms in human heart
O I Shamraj1, D Melvin, J B Lingrel
1Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati, College of Medicine, Ohio 45267-0524.
Biochemical and Biophysical Research Communications
|September 30, 1991
Abstract:
The expression pattern of the multiple isoforms of Na,K-ATPase was examined in the human heart. Isoform specific oligonucleotide probes for the alpha 1, alpha 2, alpha 3 and beta 1 subunits were used to probe Northern blots. The adult human ventricle expresses mRNAs for all three alpha subunit isoforms in addition to beta 1 subunit mRNA.