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[Legionnaire's disease outbreak].

M Pilar Barrufet-Barqué1, Goretti Sauca-Subias, Lluís Force-Sanmartín

  • 1Servicio de Medicina Interna, Hospital de Mataró, Mataró, Barcelona, Spain. pbarrufet@csm.scs.es

Medicina Clinica
|March 31, 2006
PubMed
Summary

An outbreak of Legionella pneumophila serogroup 1 in Mataró affected 151 individuals, primarily linked to a contaminated cooling tower. Prompt diagnosis and treatment contributed to low mortality in this Legionnaires' disease outbreak.

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Area of Science:

  • Epidemiology
  • Microbiology
  • Public Health

Context:

  • A significant outbreak of Legionella pneumophila serogroup 1 occurred in Mataró, Catalunya, Spain, in August 2002.
  • The identified source was a contaminated cooling tower, highlighting environmental risks.

Purpose:

  • To describe the epidemiological, clinical, and microbiological features of the Legionella outbreak.
  • To identify the causative agent and its source for public health intervention.

Summary:

  • The outbreak affected 151 individuals, with 144 cases of Legionnaires' disease pneumonia and 7 of Pontiac Fever. Key symptoms included fever, chills, and muscular pain. Antigenuria testing was highly effective (76% confirmation), and molecular analysis confirmed the cooling tower as the source.
  • Risk factors included smoking (40%) and comorbidities like diabetes mellitus (22%). Severe illness was observed in 43% of patients.

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  • Legionella spp. was isolated from respiratory secretions in 10 patients, enabling molecular confirmation of clonality with the cooling tower isolate.
  • Impact:

    • This investigation facilitated the prompt identification of the environmental source, enabling control measures.
    • The study underscores the importance of antigenuria testing for rapid diagnosis in Legionnaires' disease outbreaks.
    • Low observed mortality suggests the effectiveness of rapid diagnosis and targeted treatment in managing Legionella outbreaks.