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Ionization state of myo-inositol 1,4,5-trisphosphate: correlation with binding properties
L Schmitt1, G Schlewer, B Spiess
1Centre de Neurochimie du CNRS, Départment de Pharmacochimie Moléculaire, Strasbourg, France.
Biochimica Et Biophysica Acta
|October 10, 1991
Abstract:
The comparison between the ionization state and the binding properties on brain membrane receptors of the synthetized myo-inositol 1,4,5-trisphosphate lead to the conclusion that the biological active species may be either the monoprotonated or the fully deprotonated trisphosphate.