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Crusted scabies: a clinical review
Kjetil Kristoffer Guldbakke1, Amor Khachemoune
1International Training Program, Harvard Medical School, Boston, MA, USA.
Journal of Drugs in Dermatology : JDD
|April 1, 2006
Summary
Crusted scabies is a severe, contagious skin infestation by mites, often seen in immunocompromised individuals. Its relevance is increasing due to immunosuppressive drugs and the HIV epidemic.
Area of Science:
- Dermatology
- Infectious Diseases
- Parasitology
Background:
- Crusted scabies is a severe form of scabies infestation.
- It typically affects immunocompromised patients.
- The condition is becoming more prevalent due to increased immunosuppression and the HIV epidemic.
Purpose of the Study:
- To review the pathogenesis of crusted scabies.
- To outline the clinical manifestations.
- To discuss diagnostic and therapeutic strategies.
Main Methods:
- Literature review of published cases and research.
- Analysis of existing data on pathogenesis, clinical presentation, diagnosis, and treatment.
Main Results:
- Crusted scabies involves millions of mites, leading to generalized, severe skin lesions.
- Diagnosis is crucial, especially in at-risk populations.
- Over 200 cases have been documented.
Conclusions:
- Crusted scabies requires prompt recognition and management.
- Understanding its pathogenesis aids in developing effective treatments.
- This review provides a comprehensive overview for clinicians.