Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Acid-base balance: part II. Pathophysiology.

J McNamara1, L I Worthley

  • 1Department of Critical Care Medicine, Flinders Medical Centre, Adelaide, South Australia.

Critical Care and Resuscitation : Journal of the Australasian Academy of Critical Care Medicine
|April 1, 2006
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Healthcare provider perceptions of safety culture: A multi-site study using the safety attitudes questionnaire.

Exploratory research in clinical and social pharmacy·2023
Same author

Rad Chat letter to the editor.

Radiography (London, England : 1995)·2023
Same author

Risk of malignancy in thyroid nodules with indeterminate (THY3f) cytology.

Annals of the Royal College of Surgeons of England·2022
Same author

Gender diversity in therapeutic radiography: A mixed methods exploration of the gender influences impacting on male students' career choices.

Radiography (London, England : 1995)·2022
Same author

Challenges in recruitment and retention: Securing the therapeutic radiography workforce of the future.

Radiography (London, England : 1995)·2019
Same author

A randomized controlled trial comparing tapentadol with oxycodone in non-breastfeeding women post elective cesarean section.

Current medical research and opinion·2018

Understanding human acid-base balance is crucial. Acid-base disturbances, classified as metabolic or respiratory, are managed by addressing the underlying cause to restore normal bicarbonate and carbon dioxide levels.

Area of Science:

  • Human physiology
  • Medical biochemistry
  • Renal and respiratory regulation

Background:

  • Acid-base balance is critical for cellular function.
  • Disruptions can arise from metabolic or respiratory origins.
  • Normal physiology involves complex buffering and compensatory mechanisms.

Purpose of the Study:

  • To review normal human acid-base physiology.
  • To detail the pathophysiology of acid-base disturbances.
  • To outline management strategies for these imbalances.

Main Methods:

  • Literature review of peer-reviewed articles and abstracts.
  • MEDLINE search of English language literature from 1990-2000.
  • Focus on acid-base balance and related disorders.

Related Experiment Videos

Main Results:

  • Disorders classified as metabolic (bicarbonate) or respiratory (carbon dioxide).
  • Metabolic acidosis: increased anion gap or HCO3- loss; requires treating acid generation/enhancing clearance.
  • Metabolic alkalosis: excess HCO3- generation; requires treating causative processes.

Conclusions:

  • Acid-base disturbances are metabolic or respiratory.
  • Correcting the underlying disorder allows the body to normalize acid-base status.
  • Restoration of bicarbonate and PCO2 balance is key.