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Expanding Cytotoxic T Lymphocytes from Umbilical Cord Blood that Target Cytomegalovirus, Epstein-Barr Virus, and Adenovirus
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Published on: May 7, 2012

Immunotherapy with virus-specific cytotoxic T lymphocytes after organ transplantation

Kenneth G Lucas1, Qi Sun

  • 1Penn State Children's Hospital, Hershey, PA 17033, USA. klucas@psu.edu

Pediatric Transplantation
|April 1, 2006
PubMed

Adoptive immunotherapy with antigen specific cytotoxic T lymphocytes can favorably impact the outcome of serious herpesvirus infections in organ transplant recipients. Current challenges in this field include the determination of which patients are at highest risk, and the development of protocols that permit more rapid expansion of virus specific effector cells.

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