Related Experiment Video
Updated: Aug 9, 2026
A Protocol to Set Up Needle-Free Connector with Positive Displacement on Central Venous Catheter in Intensive Care Unit
Published on: July 13, 2019
Developing a Research base for Intravenous Peripheral cannula re-sites (DRIP trial). A randomised controlled trial of
Joan Webster1, Sophia Lloyd, Tracey Hopkins
1Centre for Clinical Nursing, Royal Brisbane and Women's Hospital, Herston, QLD 4029, Australia. joan_webster@health.qld.gov.au
Background:
There is currently no high grade evidence on which to base decisions about the frequency of intravenous cannula re-sites.
Objective:
To assess the safety of changing peripheral venous cannulas when clinically indicated.
Design:
Randomised controlled trial.
Setting:
A tertiary referral hospital in Brisbane, Australia.
Participants:
Two hundred and six hospitalised patients from surgical, medical and orthopaedic wards.
Interventions:
Peripheral intravenous cannulas were re-sited only when complications occurred (intervention group) or every 3 days (control group).
Main Outcome Measures:
The primary endpoint was any unplanned cannula removal, the secondary outcome was cost.
Results:
Forty six patients had unplanned removals in the intervention group compared with 41 in the control group [relative risk 1.12, 95% confidence interval 0.81-1.55 (p=0.286)], a non-significant difference. Total duration of peripheral cannulation was similar in both groups (mean 123.3h in the intervention group and 125.9h in the control group: P=0.82) but significantly more re-sites occurred in the control group (167 in intervention group, 202 in the control group: p=0.022). Cost of cannula replacements in the intervention group was AUD$3,183.62 and in the control group AUD$3,837.56 (p=0.006).
Conclusion:
Re-siting peripheral venous cannulas when clinically indicated compared with changing them routinely every 3 days does not lead to more complications and reduces costs.
Related Concept Videos
01:27Parentral Nutrition: Centeral and Peripheral Parental Nutrition
PN can be administered through two primary routes:
1. Central Parenteral Nutrition (CPN):
CPN involves delivering a high concentration of nutrients through a large vein. This is typically achieved using a Peripherally Inserted Central Catheter (PICC) or,...
01:16Local Anesthetics: Clinical Application as Intravenous Regional Anesthesia
One of the advantages of...