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Stem Cell-Derived Viral Ag-Specific T Lymphocytes Suppress HBV Replication in Mice
Published on: September 25, 2019
Recombinant hepatitis B large surface antigen, successfully produced in Escherichia coli, stimulates T-cell response
Li Shu1, Neal Touzjian, Deng Nan
1Nankai University Vaccine Laboratory, Nankai University, Tianjin, China.
Vaccine
|April 1, 2006
Abstract:
A fusion protein consisting of the PA binding domain of anthrax lethal factor (LFn) and a codon optimized Hepatitis B virus large surface antigen (LHBsAg) expresses well in Escherichia coli. The LFn-LHBsAg fusion protein effectively elicits a cell-mediated immune (CMI) response to the hepatitis B viral antigens in mice.
