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Updated: Aug 7, 2026

Real-time Monitoring of Ligand-receptor Interactions with Fluorescence Resonance Energy Transfer
Published on: August 20, 2012
Impact of a conformationally restricted receptor on the BF2 chelated azadipyrromethene fluorosensing platform
John Killoran1, Donal F O'Shea
1Centre for Synthesis and Chemical Biology, Conway Institute, School of Chemistry and Chemical Biology, University College Dublin, Belfield, Dublin 4, Ireland.
Abstract:
Conformational control of the receptor-fluorophore orientation of BF2 chelated azadipyrromethene sensors reveals two photophysically different modes of analyte triggered fluorescence switching both of which exhibit large off-on fluorescence intensity responses to the light input-output of the sensors in the visible red spectral region.
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