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A Quantitative Study of Cutaneous Analgesia Produced by Various Opium Alkaloids

D I Macht1, N B Herman, C S Levy

  • 1Pharmacological Laboratory, Johns Hopkins University.

Proceedings of the National Academy of Sciences of the United States of America
|December 1, 1915
PubMed
Abstract

No abstract available in PubMed .

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Pain is critical to various clinical pathologies, provoking an urgent need for effective management. Pain, whether acute or chronic, is a complex neurochemical process. Its alleviation depends on the type, with nonopioid analgesics effective for mild to moderate pain, such as musculoskeletal or inflammatory pain, while neuropathic pain responds best to anticonvulsants, tricyclic antidepressants, or serotonin/norepinephrine reuptake inhibitors. For severe acute or chronic pain, opioids may be...