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Related Experiment Videos

[Metastasis to the ENT area].

D Knöbber1, V Jahnke

  • 1HNO-Klinik, Universitätsklinikum Rudolf Virchow.

HNO
|July 1, 1991
PubMed
Summary

Metastases can mimic primary tumors in the ENT region. This study highlights three cases of amelanotic melanoma, uterine cervix carcinoma, and liver carcinoma metastasizing to the head and neck.

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Area of Science:

  • Oncology
  • Otorhinolaryngology
  • Pathology

Background:

  • Metastatic disease to the head and neck can present insidiously.
  • Distinguishing metastatic lesions from primary head and neck malignancies is crucial for appropriate treatment.

Observation:

  • Three patients presented with ENT symptoms suggestive of primary tumors.
  • Case 1: A 36-year-old woman with vertigo, hearing loss, and facial palsy had a metastasis from amelanotic melanoma.
  • Case 2: A 38-year-old woman with dysphagia had a tongue metastasis from uterine cervix carcinoma.
  • Case 3: A patient with epistaxis had a nasal cavity metastasis from liver carcinoma.

Findings:

  • Histological examination confirmed metastases in all three cases.
  • Amelanotic melanoma, uterine cervix carcinoma, and liver carcinoma were identified as primary sources.
  • Imaging confirmed the primary tumor sites in two cases (liver, uterine cervix).

Implications:

  • Early recognition of ENT metastases is vital for accurate diagnosis and management.
  • Metastatic disease to the head and neck requires a high index of suspicion.
  • This underscores the importance of thorough patient history and comprehensive diagnostic workup for seemingly primary ENT lesions.

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