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Updated: Aug 9, 2026
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Published on: February 27, 2026
Poor results after surgery for bronchioloalveolar carcinoma
R A M Damhuis1, P R Schütte, O C M Varin
1Rotterdam Cancer Registry, The Netherlands. damhuis@ikr.nl
Background:
Bronchioloalveolar carcinoma (BAC) is suggested to be less aggressive than other types of lung cancer. To assess the option of treatment modification, actual outcome data were studied and compared with results for other types of lung cancer.
Method:
Retrospective analysis of all consecutive patients who underwent resection for stage I lung cancer in our hospital. For 18 BAC cases, histological specimens were re-evaluated and in three cases diagnosis was revised.
Results:
In the period 1989 through 2000, 15 patients with BAC and 260 patients with other tumour types underwent surgery in our hospital. Five-year survival rates were 24 and 53%, respectively, (p = 0.01).
Conclusions:
Given the poor results after standard surgery, parenchyma-sparing operations do not seem justified in patients with invasive BAC.
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