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Updated: Aug 9, 2026

Capturing Actively Produced Microbial Volatile Organic Compounds from Human-Associated Samples with Vacuum-Assisted Sorbent Extraction
Published on: June 1, 2022
Analysing selected VVOCs in indoor air with solid phase microextraction (SPME): a case study
1Unit for Environmental and Hospital Hygiene, University Hospital Schleswig-Holstein, Kiel, Brunswiker Strasse 4, 24105 Kiel, Germany. mhippelein@hygiene.uni-kiel.de
Abstract:
A multi-storey building with great diversity of room use was monitored after extensive renovation to remove mould growth secondary to a leaky roof. Tests for volatile organic compounds (VOC) with activated charcoal showed a successfully renovation. Solid phase microextraction (SPME) for detection of selected very volatile organic compounds (VVOCs) revealed indoor air concentrations ranging from 550 to 4,600 microg m(-3). The SPME technique also successfully detected emissions from working and building materials and documented the results of remedial measures in offices. The prior and current use of acetone, methyl acetate and 2-methylpentane within the building resulted in their elevated concentrations in other building floors.

