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Updated: Aug 9, 2026

Repeated Measurement of Respiratory Muscle Activity and Ventilation in Mouse Models of Neuromuscular Disease
Published on: April 17, 2017
Spinal decompensation in neuromuscular disease
Jan-Willem M Kouwenhoven1, Peter M Van Ommeren, Hans E J Pruijs
1Department of Orthopedics, University Medical Center Utrecht, Utrecht, The Netherlands.
Study Design:
In this retrospective radiography study, we analyzed curve shape and direction in scoliosis secondary to neuromuscular disease.
Objective:
To determine if in different types of neuromuscular scoliosis a predominant curve pattern can be found and if similarities with idiopathic scoliosis exist.
Summary Of Background Data:
To the authors' knowledge, systematic analysis of curve patterns in patients with neuromuscular scoliosis has not been performed in a group of this size and composition.
Methods:
Spinal full-length radiographs of 198 patients with neuromuscular scoliosis were analyzed for curve shape and direction. Patients were divided into 4 groups consisting of Duchenne muscular dystrophy, cerebral palsy, spinal muscular atrophy, and spina bifida.
Results:
The results of this study show a predominance of right-sided thoracic and thoracolumbar curves, and left-sided lumbar curves, which differed significantly from an equal right-left distribution. Apical levels were respectively at T8, T12/L1 disc, and L2.
Conclusion:
In neuromuscular scoliosis, curve patterns and apical levels are similar to what is seen in the most prevalent types of adolescent idiopathic scoliosis.
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