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Updated: Aug 9, 2026
Sectioning Mammary Gland Whole Mounts for Lesion Identification
Published on: July 24, 2017
Sclerosing lobular hyperplasia of breast: cytomorphologic and histomorphologic features: a case report
Payal Kapur1, Dinesh Rakheja, Dominick C Cavuoti
1Department of Pathology, University of Texas Southwestern Medical Center, Dallas, TX, USA. payal.kapur@utsouthwestern.edu
Background:
Mammary sclerosing lobular hyperplasia is an uncommon benign lesion of adolescent and young women. Fine-needle aspiration cytology of mammary sclerosing lobular hyperplasia is said to show characteristic features that include an absence of stromal fragments.
Case Presentation:
In this article, we describe a case of sclerosing lobular hyperplasia that occurred in the right breast of a 12-year-old girl. Fine-needle aspiration cytology showed some fibroadenoma-like features including the presence of stromal fragments, while branched tubular fragments were not seen. The diagnosis of sclerosing lobular hyperplasia was made on histologic examination that showed preserved acinar architecture with lobular hyperplasia and sclerosis of intralobular and interlobular stroma.
Conclusion:
Fine-needle aspiration cytology features of mammary sclerosing lobular hyperplasia are not diagnostic and overlap with those of fibroadenoma; however, a distinction between the two benign entities is of no clinical significance. The definitive diagnosis of sclerosing lobular hyperplasia requires histopathologic evaluation.
