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Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
Published on: December 11, 2017
Complications of cardiac resynchronization therapy in patients with congestive heart failure
Hong-xia Niu1, Wei Hua, Fang-zheng Wang
1Centre of Arrhythmia Diagnosis and Treatment, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.
Insights
Cardiac resynchronization therapy (CRT) is a viable treatment for heart failure patients with conduction delays. While left ventricular lead implantation via the coronary sinus has a high success rate, procedural complications can occur.
Area of Science:
- Cardiology
- Electrophysiology
- Medical Devices
Background:
- Congestive heart failure (CHF) patients with intraventricular conduction delay may benefit from cardiac resynchronization therapy (CRT).
- Left ventricular (LV) lead implantation is a critical and complex component of CRT.
- Analysis of complications associated with LV lead implantation in CHF patients is essential.
Purpose of the Study:
- To analyze the procedural complications of CRT in patients with congestive heart failure.
- To evaluate the safety and feasibility of left ventricular lead implantation via the coronary sinus.
Main Methods:
- 117 patients with CHF and intraventricular conduction delay were enrolled.
- Venography was performed on all participants.
- Various coronary sinus leads were utilized for LV pacing.
Main Results:
- Successful LV lead implantation was achieved in 111 out of 117 patients (94.9% success rate).
- The overall complication rate was 6.8%.
- Specific complications included coronary sinus dissection (4 patients), phrenic nerve stimulation (2 patients), and lead dislodgement (2 patients).
Conclusions:
- Left ventricular pacing through the coronary sinus is a feasible and safe procedure for CHF patients.
- Despite high success rates, procedural complications necessitate careful monitoring and management.
Background:
Previous clinical studies have suggested that patients with congestive heart failure and intraventricular conduction delay could benefit from cardiac resynchronization therapy (CRT). Implantation of left ventricular lead is a complex procedure with some potential for complications. This study was conducted to analyse the complications of CRT in patients with congestive heart failure.
Methods:
Totally 117 patients, 86 males and 31 females, mean age of 53 years, with congestive heart failure and intraventricular conduction delay were enrolled in this study. Venography was performed on all patients. Different types of coronary sinus leads were used to pace the left ventricle.
Results:
Left ventricular lead was attempted to implant through coronary sinus for all the 117 patients and was successfully implanted in 111 patients. The success rate was 94.9%. Main complications rate was 6.8%, including coronary sinus dissection in 4 patients, phrenic nerve stimulation required lead repositioning in 2 patients and lead dislodgement in 2 patients.
Conclusions:
It is feasible and safe to pace left ventricle through coronary sinus. However, there are some procedural complications.
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