Complications of cardiac resynchronization therapy in patients with congestive heart failure

Hong-xia Niu1, Wei Hua, Fang-zheng Wang

  • 1Centre of Arrhythmia Diagnosis and Treatment, Fuwai Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100037, China.

Insights

Cardiac resynchronization therapy (CRT) is a viable treatment for heart failure patients with conduction delays. While left ventricular lead implantation via the coronary sinus has a high success rate, procedural complications can occur.

Area of Science:

  • Cardiology
  • Electrophysiology
  • Medical Devices

Background:

  • Congestive heart failure (CHF) patients with intraventricular conduction delay may benefit from cardiac resynchronization therapy (CRT).
  • Left ventricular (LV) lead implantation is a critical and complex component of CRT.
  • Analysis of complications associated with LV lead implantation in CHF patients is essential.

Purpose of the Study:

  • To analyze the procedural complications of CRT in patients with congestive heart failure.
  • To evaluate the safety and feasibility of left ventricular lead implantation via the coronary sinus.

Main Methods:

  • 117 patients with CHF and intraventricular conduction delay were enrolled.
  • Venography was performed on all participants.
  • Various coronary sinus leads were utilized for LV pacing.

Main Results:

  • Successful LV lead implantation was achieved in 111 out of 117 patients (94.9% success rate).
  • The overall complication rate was 6.8%.
  • Specific complications included coronary sinus dissection (4 patients), phrenic nerve stimulation (2 patients), and lead dislodgement (2 patients).

Conclusions:

  • Left ventricular pacing through the coronary sinus is a feasible and safe procedure for CHF patients.
  • Despite high success rates, procedural complications necessitate careful monitoring and management.
Abstract

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