Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitamin D therapy in psoriasis.

O E Araugo1, F P Flowers, K Brown

  • 1Department of Pharmacy Practice, College of Pharmacy, University of Florida, Gainesville.

DICP : the Annals of Pharmacotherapy
|July 1, 1991
PubMed
Summary

Topical vitamin D3 analogs offer a promising psoriasis treatment, showing faster clinical improvement and fewer side effects than oral forms. Studies confirm significant lesion reduction with topical application.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pancreatic panniculitis.

European journal of surgical oncology : the journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·2005
Same author

Distant cancer effects on standardised testing of peripheral vision.

The British journal of ophthalmology·2001
Same author

Persistent verrucous varicella as the initial manifestation of HIV infection.

Journal of the American Academy of Dermatology·2001
Same author

Asymptomatic eyelid papule in a 57-year-old healthy man.

Archives of dermatology·2000
Same author

A single-site mutant and revertants arising in vivo define early steps in the pathogenesis of Venezuelan equine encephalitis virus.

Virology·2000
Same author

Transient exotropia after posterior spinal fusion in a child: a new case.

Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus·2000

Area of Science:

  • Dermatology
  • Endocrinology
  • Pharmacology

Background:

  • Psoriasis is a chronic inflammatory skin condition.
  • Vitamin D3 analogs are explored for their therapeutic potential in managing psoriasis.
  • Clinical evidence on the efficacy and safety of vitamin D3 in psoriasis treatment is ongoing.

Purpose of the Study:

  • To review clinical trials on vitamin D3 for psoriasis treatment.
  • To compare the efficacy and adverse effects of topical versus oral vitamin D3 analogs.
  • To assess the overall potential of vitamin D3 analogs as a psoriasis therapy.

Main Methods:

  • Review of multiple clinical trials investigating vitamin D3 analogs for psoriasis.
  • Comparison of outcomes between topical and oral administration routes.
  • Analysis of reported patient improvement and adverse events.

Main Results:

  • Topical vitamin D3 analogs demonstrated consistently faster clinical improvement compared to oral administration.
  • Significant improvement in psoriatic lesions was observed in 68 out of 83 patients using topical vitamin D3 analogs.
  • Oral vitamin D3 analogs provided moderate improvement in 24 out of 35 patients, with potential for minimized adverse effects through specific dosing or new analogs.

Conclusions:

  • Topical vitamin D3 analogs represent a promising therapeutic option for psoriasis.
  • The topical route offers advantages in terms of speed of improvement and safety profile.
  • Further research into noncalciotropic analogs and optimized dosing may enhance the utility of vitamin D3 in psoriasis management.

Related Experiment Videos