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Isolation of mRNA coding for immunoglobulin heavy chain

R H Stevens1, A R Williamson

  • 1Department of Microbiolgy & Immunology University of California, Los Angeles, Los Angeles, California 90024.

Proceedings of the National Academy of Sciences of the United States of America
|November 1, 1975
PubMed
Summary

No abstract available in PubMed .

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Hybridoma technology is used for the large-scale production of monoclonal antibodies. Monoclonal antibodies bind to only a single antigenic determinant or epitope. Such antibodies are used in research, diagnostics, and disease therapy. The hybridoma technology established in 1975 by Georges Köhler and Cesar Milstein was awarded the Nobel Prize in Medicine in 1984 for revolutionizing research and therapy.
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