Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Regulatory RNAs in mammals.

M Szymański1, J Barciszewski

  • 1Institute of Bioorganic Chemistry of the Polish Academy of Sciences, Noskowskiego 12, 61-704 Poznan, Poland. mszyman@ibch.poznan.pl

Handbook of Experimental Pharmacology
|April 6, 2006
PubMed
Summary

Regulatory nonprotein-coding RNAs (npcRNAs) are crucial for gene expression control. These molecules modulate gene activity at transcriptional and post-transcriptional levels, impacting cellular processes.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Modification of χ_{c1}(3872) and ψ(2S) Production in pPb Collisions at sqrt[s_{NN}]=8.16  TeV.

Physical review letters·2024
Same author

Amplitude Analysis of the B^{0}→K^{*0}μ^{+}μ^{-} Decay.

Physical review letters·2024
Same author

Fraction of χ_{c} Decays in Prompt J/ψ Production Measured in pPb Collisions at sqrt[s_{NN}]=8.16  TeV.

Physical review letters·2024
Same author

Enhanced Production of Λ_{b}^{0} Baryons in High-Multiplicity pp Collisions at sqrt[s]=13  TeV.

Physical review letters·2024
Same author

Observation of Cabibbo-Suppressed Two-Body Hadronic Decays and Precision Mass Measurement of the Ω_{c}^{0} Baryon.

Physical review letters·2024
Same author

Improved Measurement of CP Violation Parameters in B_{s}^{0}→J/ψK^{+}K^{-} Decays in the Vicinity of the ϕ(1020) Resonance.

Physical review letters·2024

Area of Science:

  • Molecular Biology
  • Genetics
  • Epigenetics

Background:

  • Ribonucleic acids (RNAs) play diverse roles in cellular functions.
  • Beyond messenger RNAs, regulatory nonprotein-coding RNAs (npcRNAs) represent a significant class of molecules.
  • npcRNAs are increasingly recognized for their regulatory functions in gene expression.

Purpose of the Study:

  • To highlight the emerging understanding of regulatory nonprotein-coding RNAs (npcRNAs).
  • To detail the multifaceted roles of npcRNAs in gene expression modulation.
  • To emphasize the significance of npcRNAs in cellular differentiation and development.

Main Methods:

  • Literature review and synthesis of recent findings on npcRNAs.
  • Analysis of molecular mechanisms involving npcRNAs.
  • Comparative study of RNA functions in genetic information flow.

Main Results:

  • npcRNAs regulate gene expression at both transcriptional and post-transcriptional levels.
  • These molecules are involved in chromatin modification and transcription factor activity.
  • npcRNAs influence mRNA stability, processing, and translation.

Conclusions:

  • npcRNAs are key regulators in fundamental biological processes.
  • They play critical roles in genetic imprinting and X-chromosome dosage compensation.
  • npcRNAs are essential for differentiation and developmental pathways.

Related Experiment Videos