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Updated: Sep 1, 2026

Strategies for Study of Neuroprotection from Cold-preconditioning
Published on: September 3, 2010
[Experimental research on the cold-constitution and the heat-constitution (I)]
Abstract:
This paper reports the experimental research on the cold-constitution (CC) and the heat-constitution (HC). The authors have selected the CC and HC in Wistar rats, and have determined adenylate kinase (ADK) activities: energy charge and Na(+)-K(+)-ATPase activities in liver, the amounts of T3, T4, progesterone, testosterone and estradiol in serum, 17-KS in urine. The ADK activities were markedly different between the HC group and the CC group (P less than 0.01). The Na(+)-K(+)-ATPase activities were obvious different between the HC group and the CC group (P less than 0.05). The energy charge of the HC group has increased by 16.1% as compared with the CC group in cells. The contents of T3, T4 of the HC group were higher than the CC group (P less than 0.01). The content of progesterone of the HC group was higher than the CC group as well (P less than 0.01). The contents of E2 and 17-KS had no differences. These results indicated that differences between the CC and the HC were based on the basic metabolism and its regulators.
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