Related Experiment Video
Updated: Aug 9, 2026

A Novel Method for Involving Women of Color at High Risk for Preterm Birth in Research Priority Setting
Published on: January 12, 2018
Socioeconomic inequalities in very preterm birth rates
L K Smith1, E S Draper, B N Manktelow
1Department of Health Sciences, University of Leicester, 22-28 Princess Road West, Leicester LE1 6TP, UK. lks1@le.ac.uk
Insights
Socioeconomic inequalities in very preterm birth persist, with the most deprived individuals nearly twice as likely to experience this outcome. This persistent gap highlights the need for targeted interventions to reduce disparities in preterm birth rates.
Area of Science:
- Public Health
- Epidemiology
- Perinatal Health
Background:
- Socioeconomic status is a known determinant of adverse birth outcomes.
- Preterm birth, particularly very preterm birth, carries significant risks for infant morbidity and mortality.
Purpose of the Study:
- To quantify socioeconomic inequalities in the incidence of very preterm birth over a decade.
- To assess the persistence of these inequalities across different levels of deprivation.
Main Methods:
- Ecological study of singleton births (22-32 weeks gestation) in the Trent health region, UK (1994-2003).
- Poisson regression analysis to determine incidence rates by year and decile of deprivation (Index of Multiple Deprivation).
Main Results:
- Incidence of very preterm birth increased from 11.9 to 13.7 per 1000 births between 1994 and 2003.
- Individuals in the most deprived decile had nearly double the risk of very preterm birth (IRR 1.94) compared to the least deprived.
- This socioeconomic disparity remained consistent throughout the study period for both very preterm and extremely preterm births.
Conclusions:
- Wide and persistent socioeconomic inequalities exist in very preterm birth incidence.
- These disparities have implications for long-term infant morbidity.
- Findings support the need for targeted interventions and monitoring to address the persistent deprivation gap in perinatal health.
Aims:
To investigate the extent of socioeconomic inequalities in the incidence of very preterm birth over the past decade.
Methods:
Ecological study of all 549 618 births in the former Trent health region, UK, from 1 January 1994 to 31 December 2003. All singleton births of 22(+0) to 32(+6) weeks gestation (7 185 births) were identified from population surveys of neonatal services and stillbirths. Poisson regression was used to calculate incidence of very preterm birth (22-32 weeks) and extremely preterm birth (22-28 weeks) by year of birth and decile of deprivation (child poverty section of the Index of Multiple Deprivation).
Results:
Incidence of very preterm singleton birth rose from 11.9 per 1000 births in 1994 to 13.7 per 1000 births in 2003. Those from the most deprived decile were at nearly twice the risk of very preterm birth compared with those from the least deprived decile, with 16.4 per 1000 births in the most deprived decile compared with 8.5 per 1000 births in the least deprived decile (incidence rate ratio 1.94; 95% CI (1.73 to 2.17)). This deprivation gap remained unchanged throughout the 10-year period. The magnitude of socio-economic inequalities was the same for extremely preterm births (22-28 weeks incidence rate ratio 1.94; 95% CI (1.62 to 2.32)).
Conclusions:
This large, unique dataset of very preterm births shows wide socio-economic inequalities that persist over time. These findings are likely to have consequences on the burden of long-term morbidity. Our research can assist future healthcare planning, the monitoring of socio-economic inequalities and the targeting of interventions in order to reduce this persistent deprivation gap.
Related Concept Videos
Regression Toward the Mean
Environmental Influences on Intelligence
Development of the Oral Microbiota
Bias in Epidemiological Studies
Prevalence and Incidence
Prevalence indicates the proportion of individuals in a population who have a specific disease or health condition at a...
Relative Risk

