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Updated: Aug 9, 2026

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Investigation of Macrophage Polarization Using Bone Marrow Derived Macrophages
Published on: June 23, 2013
Modulation of macrophage function and metabolism
1Department of Pharmacological Sciences, University of Milan, Italy. Stefano.Bellosta@unimi.it
Handbook of Experimental Pharmacology
|April 7, 2006
Abstract:
Several drugs or pharmacologically active molecules such as statins, calcium antagonists, and PPAR agonists have been shown to affect macrophage functions that contribute to atherosclerosis and modulate plaque stability. For example, the modulation of matrix metalloproteinase secretion and cholesterol metabolism in macrophages may help to prevent cardiovascular disease independently of the correction of risk factors.
