Novel bicyclization reaction leading to a fused beta-lactone
Leleti Rajender Reddy1, E J Corey
1Department of Chemistry and Chemical Biology, Harvard University, 12 Oxford Street, Cambridge, Massachusetts 02138, USA.
Organic Letters
|April 7, 2006
Abstract:
[reaction: see text] The reaction of acrylyl chloride with the above amino ketone in the presence of pyridine produces bicyclic beta-lactones rather than the corresponding acrylamide, which can be the major product under other conditions.
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