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Updated: Aug 9, 2026

ampliPHOX Colorimetric Detection on a DNA Microarray for Influenza
Published on: June 9, 2011
Use of semiconductor-based oligonucleotide microarrays for influenza a virus subtype identification and sequencing
Michael J Lodes1, Dominic Suciu, Mark Elliott
1CombiMatrix Corporation, 6500 Harbour Heights Parkway, Suite 301, Mukilteo, WA 98275, USA. mlodes@combimatrix.com
Abstract:
In the face of concerns over an influenza pandemic, identification of virulent influenza A virus isolates must be obtained quickly for effective responses. Rapid subtype identification, however, is difficult even in well-equipped virology laboratories or is unobtainable in the field under more austere conditions. Here we describe a genome assay and microarray design that can be used to rapidly identify influenza A virus hemagglutinin subtypes 1 through 15 and neuraminidase subtypes 1 through 9. Also described is an array-based enzymatic assay that can be used to sequence portions of both genes or any other sequence of interest.
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