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Serous retinal detachment in a patient with aplastic anemia associated with parvovirus B19 infection
Jun Suzuki1, Hiroshi Goto, Masahiko Usui
1Department of Ophthalmology, Tokyo Medical University Hospital, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo, 160-0023, Japan. jun-s@qc4.so-net.ne.jp
Background:
We report a case of unilateral serous retinal detachment (RD) associated with parvovirus B19 infection.
Case Report:
A 28-year-old woman had a clinical history of autoimmune hemolytic anemia and pure red cell aplasia associated with parvovirus B19 infection. She demonstrated focal serous RD without retinal exudates. A focal cataract and anterior vitreous cells were also observed. Fluorescein angiography (FA) revealed accumulation of subretinal fluid, but no vascular leakage. After vitrectomy, the retina was re-attached and visual acuity returned to 20/20. IgM antibody to parvovirus and viral DNA were detected by polymerase chain reaction in the vitreous fluid obtained at surgery.
Conclusion:
To our knowledge, this is the first reported case of the presence of anti-viral IgM and viral DNA in vitreous sample. Furthermore, the ocular findings in our patient are definitively different from previously reported cases of parvovirus-associated ocular disorders.
